Influence of polyphenol-rich apple pomace extract on oxidative damage to DNA in type 2 diabetes mellitus individuals

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Influence of polyphenol-rich apple pomace extract on oxidative damage to DNA in type 2 diabetes mellitus individuals

Background Diabetes mellitus type 2 (DM2) is associated with increased oxidative stress and oxidative damage to DNA. An appropriate intake of antioxidants via the diet can improve this disturbed oxidative status [1]. Apples are the most widely consumed fruits in Europe and represent a major source of antioxidants due to their high polyphenol content [2]. Apple pomace as a polyphenol-rich byprod...

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Oxidative DNA damage and obesity in type 2 diabetes mellitus.

OBJECTIVE This study illustrates the relationship between oxidative DNA damage and obesity in patients with prediabetes and type 2 diabetes compared with controls. DESIGN AND METHODS Participants attended the School of Community Health, Diabetes Screening Clinic, Charles Sturt University, Australia, between February 2006 and June 2008. A total of 162 participants (35 type 2 diabetic patients;...

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Oxidative Stress, DNA Damage and DNA Repair in Female Patients with Diabetes Mellitus Type 2

BACKGROUND Diabetes mellitus type 2 (T2DM) is associated with oxidative stress which in turn can lead to DNA damage. The aim of the present study was to analyze oxidative stress, DNA damage and DNA repair in regard to hyperglycemic state and diabetes duration. METHODS Female T2DM patients (n = 146) were enrolled in the MIKRODIAB study and allocated in two groups regarding their glycated hemog...

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Predicting Medication Adherence Based on Personality Characteristics in Individuals with Type 2 Diabetes Mellitus

Objective: Diabetes mellitus is a chronic illness and adherence to medications is vital to manage the illness. The purpose of this study was to examine the prediction of medication adherence based on personality factors in a group of individuals with type 2 diabetes in Yasuj. Materials and Methods: One hundred twenty individuals with type 2 diabetes who visited health centers were selected for...

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Protective Effect of Hibiscus Polyphenol-rich Extract against H2o2 Induced Oxidative Damage of Human Erythrocytes

In the present study, Hibiscus rosasinensis polyphenol-rich extract (HPE) was isolated from the flowers and evaluated for its protective effect against hydrogen peroxide (H2O2) induced oxidation in normal human erythrocytes. RBCs pretreated with different concentrations of HPE extract showed the same hemolysis as that of control samples, demonstrating that the tested HPE extract did not have a ...

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ژورنال

عنوان ژورنال: Cancer & Metabolism

سال: 2014

ISSN: 2049-3002

DOI: 10.1186/2049-3002-2-s1-p25